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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUMB
All Species:
19.7
Human Site:
T631
Identified Species:
61.9
UniProt:
P49757
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49757
NP_001005743.1
651
70804
T631
E
N
K
S
K
Q
R
T
N
P
S
P
T
N
P
Chimpanzee
Pan troglodytes
XP_001150743
651
70742
T631
E
N
K
S
K
Q
R
T
N
P
S
P
T
N
P
Rhesus Macaque
Macaca mulatta
XP_001090008
652
70896
T632
E
N
K
S
K
Q
R
T
N
P
S
P
T
N
P
Dog
Lupus familis
XP_867854
658
71349
T638
E
S
K
S
K
Q
R
T
N
P
S
P
T
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS3
653
70794
T633
E
S
K
S
K
Q
R
T
N
P
S
P
T
N
P
Rat
Rattus norvegicus
A1L1I3
614
65494
A594
A
A
L
E
G
K
P
A
V
E
K
P
S
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990166
582
63254
N563
S
K
A
K
Q
R
T
N
P
S
P
T
N
P
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16554
556
60596
S537
R
S
P
L
A
R
H
S
T
N
P
F
I
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
94.8
N.A.
93.4
49.4
N.A.
N.A.
74.5
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.5
96
N.A.
94.9
59.7
N.A.
N.A.
79.4
N.A.
N.A.
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
13
0
13
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
63
0
0
13
0
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
13
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
13
63
13
63
13
0
0
0
0
13
0
0
0
0
% K
% Leu:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
38
0
0
0
0
0
13
63
13
0
0
13
75
0
% N
% Pro:
0
0
13
0
0
0
13
0
13
63
25
75
0
13
88
% P
% Gln:
0
0
0
0
13
63
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
25
63
0
0
0
0
0
0
0
0
% R
% Ser:
13
38
0
63
0
0
0
13
0
13
63
0
13
13
0
% S
% Thr:
0
0
0
0
0
0
13
63
13
0
0
13
63
0
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _